Pwodwi Entwodiksyon
| 1-Methylpiperazine Enfòmasyon de baz |
| Non pwodwi: | 1-Methylpiperazine |
| Sinonim: | N-METHYLPIPERAZINE;NMPRZ;1-methyl-piperazin;1-METHYLPIPERAZINE POU SENTÈZ; Konpozisyon A ki gen rapò siklizin;N-Methylpiperazine;4-Methylpiperazine;1-Methylpiperazine, 99+% 100GR |
| CAS: | 109-01-3 |
| MF: | C5H12N2 |
| mw: | 100.16 |
| EINECS: | 203-639-5 |
| Kategori pwodwi: | 1; Benzotriazol, Triazol; Blòk Konstriksyon; C4 a C8; Sentèz Chimik; Blòk Konstriksyon Heterocyclic; Azòt ki gen; Alpha Sort; Heterocyclics; M; MAlphabetic; META - METHChemical Klas; Volatil/ Semivolatiles; Blòk Konstriksyon Heterocyclic, Piperidones, Piperidone; ;Piperaizine;Piperazine dérivés;Piperazin;Blòk konstriksyon |
| Mol File: | 109-01-3.mol |
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| 1-Methylpiperazine Pwopriyete Chimik |
| Pwen k ap fonn | -6 degre |
| Pwen bouyi | 138 degre (lit.) |
| dansite | 0.903 g/mL nan 25 degre (lit.) |
| dansite vapè | 3.5 (kont lè) |
| presyon vapè | 12 hPa (20 degre) |
| endèks refraktif | n20/D 1.466(lit.) |
| Fp | 108 degre F |
| tanperati depo. | 2-8 degre |
| solubilite | Klorofòm (soluble), metanol (soluble) |
| pka | pK1:4.94(+2);pK2:9.09(+1) (25 degre ,μ=0.1) |
| fòm | Likid |
| Espesifik gravite | 0.903 |
| koulè | Klè |
| PH | 11-12 (50g/l, H2O, 20 degre) |
| limit eksplozif | 1.2-9.9%(V) |
| Solibilite dlo | idrosolubl |
| Sansib | Igroskopik |
| BRN | 102724 |
| InChiKey | PVOAHINGSUIXLS-UHFFFAOYSA-N |
| LogP | -0.57 nan 25 degre |
| Referans baz done CAS | 109-01-3(Referans baz done CAS) |
| Referans Chimi NIST | Piperazin, 1-metil-(109-01-3) |
| Sistèm Rejis Sibstans EPA | Piperazin, 1-metil- (109-01-3) |
| Enfòmasyon sou Sekirite |
| Kòd danje | T, F, C, Xi |
| Deklarasyon Risk | 10-21-23-34-36/37/38-20/21 |
| Deklarasyon Sekirite | 16-26-36/37/39-45-36 |
| RIDADR | UN 2734 8/PG 2 |
| WGK Almay | 2 |
| RTECS | TM1225000 |
| Tanperati Autoignition | 320 degre |
| Nòt danje | Ki ka pran dife/Toksik/Korozif/Sere anba nitwojèn |
| TSCA | Wi |
| HazardClass | 3 |
| PackingGroup | III |
| Kòd HS | 29335995 |
| Toksisite | LD50 oralman nan lapen: 2547 mg/kg LD50 po lapen 1341 mg/kg |
| Enfòmasyon MSDS |
| Founisè | Lang |
|---|---|
| 1-Methylpiperazine | angle |
| ACROS | angle |
| SigmaAldrich | angle |
| ALFA | angle |
| 1-Methylpiperazine Itilizasyon ak sentèz |
| Pwopriyete chimik | likid klè |
| Itilizasyon | 1-Methylpiperazine yo itilize nan preparasyon 2-(4-Methyl-1-piperazinylmethyl)acrylophenone (MPMAP) |
| Itilizasyon | 1-Methylpiperazine yo itilize nan preparasyon 2-(4-methyl-1-piperazinylmethyl)acrylophenone. Li patisipe nan preparasyon 1-(4-metoksi-fenil)-4-methyl-piperazine nan reyaji ak 1-kloro-4-metoksi-benzèn. Li aji kòm yon entèmedyè nan sentèz engredyan pharmaceutique aktif tankou ofloxacin, rifampicin, clozapine, sildenafil, trifluoperazine ak zopiclone. Anplis de sa, li se itilize kòm yon modèl imite nan preparasyon an nan mikrosfè molekilè anprint. Anplis de sa, li se itilize nan jenerasyon an nan faz estasyonè echanj aniyon fò difonksyonèl soti nan yon dérivé 1,4-diazacyclohexane. |
| Definisyon | ChEBI: 1-Methylpiperazine se yon N-methylpiperazine. |
| Danje | Modere risk dife. |
| Enflamabilite ak eksplozibilite | Ki ka pran dife |
| Pwofil sekirite | Pwazon pa wout intraperitoneal. Modere toksik pa rale, enjèstyon, ak kontak po. Yon irite grav pou po ak je. Likid ki ka pran dife lè yo ekspoze a chalè oswa flanm dife; ka reyaji ak materyèl oksidan. Pou konbat dife, sèvi ak bave alkòl, CO2, pwodui chimik sèk. Lè chofe pou dekonpozisyon li emèt lafimen toksik NOx. |
| 1-Methylpiperazine Preparasyon Pwodui Ak Matyè Bwit |
| Matyè premyè | Methanol-->Carbon dioxide-->Piperazine-->PIPERAZINE HEXAHYDRATE-->PIPERAZINE DIHYDROCHLORIDE |
| Preparasyon pwodwi yo | Zopiclone-->2-(4-Methylpiperazin-1-yl)pyrimidine-5-carbaldehyde-->3-[(4-METHYLPIPERAZIN-1-YL)METHYL]BENZALDEHYDE-->2-(4-Methylpiperazin-1-yl)pyrimidine-5-carboxamide-->2-(4-Methylpiperazin-1-yl)pyrimidin-5-amine-->(2-(4-Methylpiperazin-1-yl)pyrimidin-5-yl)methanol-->2-(4-Methylpiperazin-1-yl)pyrimidine-5-carbonyl chloride-->(3,4-DIAMINO-PHENYL)-(4-METHYL-PIPERAZIN-1-YL)-METHANONE-->2-(4-Methylpiperazin-1-yl)pyrimidine-5-carboxylic acid-->2-(4-Methylpiperazin-1-yl)pyrimidine-5-carbonitrile-->3-(4-Methylpiperazin-1-ylmethyl)benzoic acid-->Ethyl 2-(4-methylpiperazin-1-yl)pyrimidine-5-carboxylate-->4-[(4-Methylpiperazin-1-yl)methyl]aniline-->(2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidin-4-yl)methanamine-->CHLORCYCLIZINE HYDROCHLORIDE-->2-Hydrazinyl-1-(4-methylpiperazin-1-yl)ethanone-->3-Hydrazinyl-1-(4-methylpiperazin-1-yl)propan-1-one-->CHLORCYCLIZINE-->2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carbaldehyde-->Levofloxacin-->2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carboxamide-->(2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidin-4-yl)methanol-->2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidin-4-amine-->2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carbonitrile-->4-(4-Methylpiperazino)aniline-->2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carboxylic acid-->1-METHYL-4-(4-NITROPHENYL)PIPERAZINE-->Ethyl 2-(4-methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carboxylate-->4-(4-METHYLPIPERAZINOMETHYL)BENZOIC ACID-->(4-METHYL-PIPERAZIN-1-YL)-ACETIC ACID-->Clozapine-->1-METHYL-4-(3-NITROPHENYL)PIPERAZINE-->1-AdaMantanethylaMine-->1-METHYL-4-(4-NITROBENZYL)PIPERAZINE-->1-Amino-4-methylpiperazine-->1-FORMIL-4-METHYLPIPERAZINE |
Baj popilè: 1-methylpiperazine, Lachin 1-methylpiperazine manifaktirè, founisè, faktori
On: 1-Etilpiperazin
Pwochen: 2-Methylpiperazine
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