![2-Azabicyclo[2.2.1]hept{{4}en-3-one](/uploads/41226/2-azabicyclo-2-2-1-hept-5-en-3-one31fa0.gif)
Pwodwi Entwodiksyon
| 2-Azabicyclo[2.2.1]hept-5-en-3-one Enfòmasyon de baz |
| Non pwodwi: | 2-Azabicyclo[2.2.1]hept{{4}en-3-one |
| Sinonim: | (+/-)-2-Azabicyclo[2.2.1]hept-;2-AZABICYCLO(2.2.1)HEPT-5-EN-3-ONE, (VINCE LACTAM);{ {13}}Azabicyclo(2,2,1,)hept-5-en-3-on;Vince Lactam (2-azabicyclo[2.2.1]hept-5-en{{ 24}}yon);2-AZABICYCLO(2.2.1)HEPT-5-EN-3-YON, 99% (VINCE LACTAM);(±)-2-Azabicyclo[2.2. 1]hept-5-en-3-yon sèl, 4-Amino-2-cyclopentene-1-carboxylic acid lactam;3-Azabicyclo[2.2.1]hepta{ {45}}ene-2-one;(±)-2-Azabicyclo[2.2.1]hept-5-en-3-one,98% |
| CAS: | 49805-30-3 |
| MF: | C6h7no |
| mw: | 109.13 |
| EINCS: | 421-830-3 |
| Kategori pwodwi: | Dérivés klori Cyanogen; Dérivés asid idrosyanik; (entèmedyè abacavir); Eterosikl; Entèmedyè; Sistèm bag fusion;3 |
| Mol File: | 49805-30-3.mol |
![2-Azabicyclo[2.2.1]hept-5-en-3-one Structure](https://www.chemicalbook.com/CAS/GIF/49805-30-3.gif "product-1-1") |
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| 2-Azabicyclo[2.2.1]hept-5-en-3-one Chimik Pwopriyete |
| Pwen k ap fonn | 54-58 degre (lit.) |
| Pwen bouyi | {{0}} degre 0.25 mm Hg (lit.) |
| dansite | 1.1143 (estimasyon ki graj) |
| presyon vapè | 0.3-1.06Pa nan 25-40 degre |
| endèks refraktif | 1.5040 (estimasyon) |
| Fp | >230 degre F |
| tanperati depo. | Kenbe nan yon kote ki fè nwa, sele nan sèk, Tanperati chanm |
| solubilite | idrosolubl nan metanol |
| pka | 15.48±0.20(Prevwa) |
| fòm | Crystalline poud |
| koulè | Off-blan a bèlj |
| Solibilite dlo | >1000 g/L (23 ºC) |
| retni | 508342 |
| InChiKey | DDufyknoxPZZIW-UHFFFAOYSA-N |
| Boutèy demè | -0.14 nan 20 degre |
| Tansyon sifas yo | 69.9mN/m nan 1g/L ak 20 degre |
| Referans baz done CAS | 49805-30-3(Referans baz done CAS) |
| Enfòmasyon sou Sekirite |
| Kòd danje | Xi, Xn |
| Deklarasyon Risk | 36/37/38-43-22 |
| Deklarasyon Sekirite | 26-36-36/37 |
| WGK Almay | 1 |
| Kòd HS | 29337900 |
| Enfòmasyon MSDS |
| Founisè | Lang |
|---|---|
| SigmaAldrich | angle |
| ATRAVÈ | angle |
| 2-Azabicyclo[2.2.1]hept-5-en-3-one Itilizasyon ak sentèz |
| Pwopriyete chimik | olid |
| Itilizasyon | Entèmedyè pou pharmaceutique. Fèy Done pwodwi |
| Itilizasyon | 2-Azabicyclo[2.2.1]hept-5-en-3-one yo te itilize nan: preparasyon pou (3kòmS,4R,6R,6r)-6-((metoxy-metoxy)methyl)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-amine, yon précurseur analòg bredinin sentèz dwòg ki ka geri ou sentèz chemoenzymatic nan (?)-carbovir |
| Itilizasyon | Abacavir entèmedyè. 2-Azabicyclo[2.2.1]hept-5-en-3-one yo itilize kòm yon entèmedyè nan sentèz amine sik carbocyclic, carbanucleosides, ak analogue dinukleotid carbocyclic. |
| Deskripsyon jeneral | 2-Azabicyclo[2.2.1]hept-5-en-3-one yo rele tou vince laktam. Li se yon entèmedyè versatile nan sentèz nukleozid carbocyclic. 2-Azabicyclo[2.2.1]hept-5-en-3-one ak konplèks monoidrat li yo te envestige nan yon jè sipèsonik pa espektroskopi mikwo ond transfòmasyon Fourier. |
| 2-Azabicyclo[2.2.1]hept-5-en-3-one Preparasyon pwodwi ak matyè premyè |
| Matyè premyè | Sodium hydroxide-->Dichloromethane-->Acetic acid-->PETROLEUM ETHER-->Magnesium sulfate-->1,3-Cyclopentadiene-->Dicyclopentadiene-->Tosyl cyanide |
| Preparasyon pwodwi yo | (-)-(1S,4R)-4-AMINOCYCLOPENT-2-ENECARBOXYLIC ACID-->((1R,4S)-2-Azabicyclo[2.2.1]hept-5-en-3-one-->RaceMic tert-butyl 3,6-diazabicyclo[3.2.1]octane-6-carboxylate-->(1S-cis)-4-Amino-2-cyclopentene-1-methanol-->Tert-Butyl2-azabicyclo[2.2.1]hept-5-ene-2-carboxylate-->(+)-(1S,3R)-N-BOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID-->5,6-Dihydroxy-2-Azabicyclo[2.2.1]Heptan-3-One-->1-Siklopentèn-1-asid karboksilik, 4-[[(1,{1-diMethylethoxy)carbonyl]aMino]-, Methyl ester |
Baj popilè: 2-azabicyclo[2.2.1]hept-5-en-3-one, Lachin 2-azabicyclo[2.2.1]hept-5-en-3-one manifaktirè, founisè, faktori
On: Non
Pwochen: 2-(tèt-Butylamino)etil metakrilat
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