4'-Methyl-2-cyanobiphenyl

4'-Methyl-2-cyanobiphenyl

Pwodwi Entwodiksyon

 
4'-Methyl-2-cyanobiphenyl Enfòmasyon debaz
Non pwodwi: 4'-Methyl-2-cyanobiphenyl
Sinonim: methyl diphenyl;2-syanojèn radikal-4'-methyl biphenyl;2-[({4-methyl)pentyl]-benzonitrile;OTBN;4'-Methyl-2- Cyano Diphenyl;AKOS BAR-1203;4'-METHYLBIPHENYL-2-KARBONITRIL;4'-METHYL-2-BIFENILKARBONITRIL
CAS: 114772-53-1
MF: C14H11N
mw: 193.24
EINCS: 422-310-9
Kategori pwodwi: Biphenyl & Diphenyl etè; (entèmedyè nan telmisartan); Biphenyl dérivés; (entèmedyè nan sartan); (entèmedyè nan pwodwi sartan); Losartan Potasyòm; Kòmanse matyè premyè & Entèmedyè; Elektwonik òganik ak fotonik;syanid;114772-53-1
Mol File: 114772-53-1.mol
4'-Methyl-2-cyanobiphenyl Structure
 
Pwopriyete chimik 4'-Methyl-2-cyanobiphenyl
Pwen k ap fonn 49 degre
Pwen bouyi >320 degre
dansite 1,17 g / cm3
presyon vapè 0.014Pa nan 20 degre
Fp >320 degre
tanperati depo. Sele nan sèk, Tanperati chanm
solubilite Chloroform (yon ti kras), metanol (yon ti kras)
fòm Crystalline poud
koulè Off-blan a bèlj
BRN 3605954
pous InChi{{0}S/C14H11N/c1-11-6-8-12({{}{14-5-3-2-4-13}(14)7b{7{7}}{{8{8}H
InChiKey ZGQVZLSNEBEHFN-UHFFFAOYSA-N
SOURI C1(C{{1}CC{{2}C(C)C{{3}C2)=CC{{{6{6}CC{{{{{7}C1C#N
Boutèy demè 3.5 nan 23 degre
Referans baz done CAS 114772-53-1(Referans baz done CAS)
Referans Chimi NIST Benzonitril, 2-(4-metilfenil)-(114772-53-1)
 
Enfòmasyon sou Sekirite
Kòd danje Xn, Xi
Deklarasyon Risk 20/21/22-36/37/38-48/25/62/51/53-22
Deklarasyon Sekirite 22-26-36/37/39-36/37/45/57-20-36
WGK Almay 3
Nòt danje Iritant
Kòd HS 27075000
 
Enfòmasyon MSDS
Founisè Lang
2-Cyano-4'-methylbiphenyl angle
ATRAVÈ angle
ALFA angle
 
4'-Methyl-2-cyanobiphenyl Itilizasyon ak sentèz
Pwopriyete chimik Blan cristalline poud
Itilizasyon 4'-Methylbiphenyl-2-karbonitrile se yon entèmedyè nan sentèz glikojèn sintaz kinaz-3 inhibiteurs ak yon pike selektif pou glikojèn sintaz kinaz 3 .
Sentèz 4'-Methyl-2-cyanobiphenyl prepare pa reyaksyon o-cyanobromobenzene ak potasyòm ({4-methylphenyl)trifluoroborate. Etap espesifik sentèz yo se jan sa a:
Pwosedi jeneral: Yon melanj de alogen aryl ({{0}}.5 mmol), aryltrifluoroborate potasyòm (0.6 mmol), K2CO3 (1.{0 mmol), Pd/ C (5%; 0.5 mol%), etanòl (3 mL), ak dlo distile (1 mL) te brase nan 80 degre nan lè pou tan ki endike a. Yo te ajoute melanj reyaksyon an nan sèl (15 mL) ak ekstrè ak acetate etil (4 × 15 mL). Yo te retire sòlvan òganik la anba vakyòm, epi yo te izole pwodwi a pa kromatografi kout kolòn.
4'-Methyl-2-cyanobiphenyl synthesis
 
4'-Methyl-2-cyanobiphenyl Preparasyon pwodwi ak matyè premyè
Matyè premyè POTASSIUM 4-METHYLPHENYLTRIFLUOROBORATE-->2-Bromobenzonitril
Preparasyon pwodwi yo 5-[4'-(Bromomethyl)-[1,1'-biphenyl]-2-yl]-2-(triphenylmethyl)-2H-tetrazole-->4'-[(2-butil-4-kloro-5-idroksimetil)-1H-imidazol-1-il)metil]-[1,1'-Bifenil] -2-karbonitril

Baj popilè: 4'-methyl-2-cyanobiphenyl, Lachin 4'-methyl-2-cyanobiphenyl manifaktirè, founisè, faktori

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