Pwodwi

Dimethyl Malonate

Pwodwi Entwodiksyon

Dimethyl malonate Enfòmasyon de baz

Non pwodwi:	Dimethyl malonate
Sinonim:	dimethyl malonate;DiMethyl Malonate, 97% 250ML;Malonic Asid Dimethyl Ester Methyl Malonate;DIMETHYL MALONATE POU SENTÈZ;Propanedioicacid, 1,3-diMethyl ester;Asid malonik d;Dimethyl malonate Vetec(TM) reaktif 98%; ESTER DIMETHYL AID PROPANEYYOIC
CAS:	108-59-8
MF:	C5H8O4
mw:	132.11
EINCS:	203-597-8
Kategori pwodwi:	Tiazol; Blòk Konstriksyon; C2 rive C5; Konpoze Carbonyl; Sentèz Chimik; Blòk Konstriksyon òganik; C2 rive C5; Konpoze Carbonyl; Estè; bc0001;108-59-8
Mol File:	108-59-8.mol

Dimethyl malonate Pwopriyete chimik

Pwen k ap fonn	-62 degre (lit.)
Pwen bouyi	180-181 degre (lit.)
dansite	1.156 g/mL nan 25 degre (lit.)
dansite vapè	>1 (kont lè)
presyon vapè	0.15 hPa (20 degre)
endèks refraktif	n20% 2FD 1.413 (lit.)
Fp	194 degre F
tanperati depo.	Sere anba +30 degre.
solubilite	alkòl: miscible
pka	11.80±0.46(Prevwa)
fòm	Likid
koulè	Klè san koulè
Odè	frwiti
limit eksplozif	1.3-17.4%(V)
Solibilite dlo	neglijab
Mèkredi	14,6096
retni	774261
Konstan Dielectric	10.4 (20 degre)
Estabilite:	Ki estab. Enkonpatib ak ajan oksidan fò. Ki ka pran dife.
InChiKey	BEPAFCGSDWSTEL-UHFFFAOYSA-N
Boutèy demè	-0.05 nan 20-25 degre ak pH6.4
Referans baz done CAS	108-59-8(Referans baz done CAS)
Referans Chimi NIST	Asid propanedioik, ester dimetil (108-59-8)
Sistèm Rejis Sibstans EPA	Dimethyl malonate (108-59-8)

Enfòmasyon sou Sekirite

Kòd danje	ksi
Deklarasyon Risk	36/37/38
Deklarasyon Sekirite	26-36
WGK Almay	1
RTÈK YO	OO0950000
Tanperati Autoignition	440 degre
Nòt danje	Iritant
tSCA	Wi
Kòd HS	29171910
Toksisite	LD50 oralman nan lapen: 5331 mg/kg LD50 po lapen > 5000 mg/kg

Enfòmasyon MSDS

Founisè	Lang
Methyl malonate	angle
Sigmaaldrich	angle
ATRAVÈ	angle
ALFA	angle

Dimethyl malonate Itilizasyon ak sentèz

Deskripsyon	Dimethyl malonate se yon derive diester nan asid malonik. Li se yon reyaktif komen pou sentèz òganik yo itilize, pou egzanp, kòm yon précurseur pou asid barbiturik. Li se tou itilize nan sentèz la ester malonik. Li ka sentèz soti nan dimethoxymethane ak monoksid kabòn.
Pwopriyete chimik	likid
Pwopriyete chimik	Dimethyl malonate se idrosolubl nan alkòl ak etè ak trè yon ti kras idrosolubl nan dlo. Li ka dekonpoze tou dousman.
Itilizasyon	Li se itilize nan parfen ak kèk arom atifisyèl.
Itilizasyon	Dimethyl malonate se yon reyaktif ki itilize nan sentèz òganik. Li aji kòm yon précurseur pou sentèz mono-ranplase ak di-ranplase asid acetic, barbituric, vitamin B1 ak vitamin B6. Yo itilize li nan endistri pharmaceutique pou prepare pharmaceutique tankou chloroquine ak butazolidin. Li patisipe nan sentèz diastereomeric pi thienylpyrididines lè li reyaji ak 1,3-diphenylprop-2-enyl acetate.
Aplikasyon	Dimethyl malonate sibi yon reyaksyon sibstitisyon alilik ki katalize paladyòm enantioselectiv ak 1,3-diphenylprop-2-enyl acetate pou bay diastereomeric pi thienylpyridines. Dimethyl malonate te itilize nan lò katalize oksidatif esterifikasyon gliserin, 1,2-propanediol ak 1,3-propanediol.
Metòd pwodiksyon	Dimethyl malonate se pwodwi atravè esterifikasyon dirèk nan metanol ak asid malonik nan kondisyon azeotropic.
Deskripsyon jeneral	Dimethyl malonate sibi yon reyaksyon sibstitisyon alilik ki katalize paladyòm enantioselectiv ak 1,3-diphenylprop-2-enyl acetate pou bay diastereomeric pi thienylpyridines.

Dimethyl malonate Preparasyon pwodwi ak matyè premyè

Matyè premyè

Hydrochloric acid-->Methanol-->Sulfuric acid-->Sodium carbonate-->Sodium cyanide-->Chloroacetic acid-->Sodium chloroacetate-->Cyanoacetic acid-->Asid MALONIK SÈL DISODIUM

Preparasyon pwodwi yo

1-AMINO-CYCLOPROPANEMETHANOL-->DIMETHYL METHOXYMALONATE-->Chlorimuron-ethyl-->3-(4-FLUOROPHENYL)PROPIONIC ACID-->ADS-->TERT-BUTYL METHYL MALONATE-->2-Methylpyrimidine-->Methyl 3-cyclopentenecarboxylate-->Sethoxydim-->Primisulfuron-methyl-->8-METHOXY-2-OXO-2H-CHROMENE-3-CARBOXYLIC ACID AMIDE-->7-HYDROXY-2-OXO-2H-CHROMENE-3-CARBOXYLIC ACID AMIDE-->3-CARBETHOXY-4-HYDROXYCOUMARIN-->5-(2-ETHYLTHIO PROPYL)-1,3-CYCLOHEXANEDIONE-->6-Chlorooxindole-->Pipemidic acid-->5-Fluoro-2-oxindole-->DIMETHYL BROMOMALONATE-->7-HYDROXY-2-OXO-2H-CHROMENE-3-CARBOXYLIC ACID METHYL ESTER-->7-HYDROXY-2-OXO-2H-CHROMENE-3-CARBOXYLIC ACID METHYL ESTER-->1,1-Cyclopropanedicarboxylic acid dimethyl ester-->6-CHLORO-2-OXO-2H-CHROMENE-3-CARBOXYLIC ACID-->MALONIC ACID DI-N-BUTYL ESTER-->Dimethyl ethylmalonate-->Dimethyl chloromalonate-->5-MESITYL-1,3-CYCLOHEXANEDIONE-->{{0}(TETRAHYDRO-2H-THIOPYRAN{{3}yL){-1{{{5{5}}CYCLOHEXANEDIONE

Baj popilè: dimethyl malonate, Lachin dimethyl malonate manifaktirè, Swèd, faktori

On: Non

Pwochen: DIETHYLENEGLYCOL METHYL-TERT-BUTYL ETHE

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